Endocrine Abstracts

Background: The thyroid pyramidal lobe (TPL) represents a normal anatomical variation of the thyroid gland. Intraoperative TPL identification is of paramount significance, taking into account that the remnant TPL leads to higher thyroglobulin, could contain thyroid carcinoma foci and lead to recurrence.Methods: We conducted a prospective single-center, single-operator study to identify TPL in 500 consecutive patients undergoing thyroid ultrasound for any...

Background: The thyroid pyramidal lobe (TPL) represents a normal anatomical variation of the thyroid gland. Intraoperative TPL identification is of paramount significance, taking into account that the remnant TPL leads to higher thyroglobulin, could contain thyroid carcinoma foci and lead to recurrence.Methods: We conducted a prospective single-center, single-operator study to identify TPL in 1275 consecutive patients undergoing thyroid ultrasound for an...

Background: Primary hypothyroidism diagnosis is mainly based on the TSH (thyroid-stimulating hormone) and free thyroxine (T4) levels. Following treatment initiation, the main lab test used for dose adjustment is TSH. However, there could be potential issues with TSH measurement.Case report: A young lady, 36, presented to our clinic in January 2019, being treated with Levothyroxine 175 mg daily, and having clinical signs and symptoms of thyrotoxicosis: ta...

Background: Primary hyperparathyroidism (PHPTH) refers to overproduction of PTH (parathyroid hormone) which leads to hypercalcaemia and hypophosphataemia. Preoperative imaging aims identification of a solitary parathyroid adenoma (PTA) or multiple gland hyperplasia. However, it is not always possible to identify the lesions, and in some situations imaging findings could be misleading.Case report: A 48-year old male, with personal history of differentiate...

Background: Hypothyroidism is defined as an elevated TSH (thyroid-stimulating hormone) and/or decreased free thyroxine (FT4) levels. Levothyroxine is now one of the most widely prescribed medications. However, treatment indications are controversial in subclinical hypothyroidism, defined as high TSH with normal T4 levels. Methods: We performed a cross-sectional study reviewing the blood samples received in our Laboratory for TSH determination during the ...

Background: Neuroendocrine tumours (NET) can affect various tissues and organs, have different clinical presentation and prognosis, depending on the primary tumour site, grading, differentiation and functional status. Reported prevalence of bone metastases (BM) from NETs has been increasing with improved imaging modalities, reaching >40% in some reports. The BM diagnosis is associated with reduced overall survival; however, this was not confirmed by all studies.<p clas...